Menopause brings many changes. It's a time when a woman's risk of heart disease starts to rise. The risk of other health problems such as osteoporosis and breast cancer also increases. Until recently, taking hormone therapy with estrogen alone or with estrogen plus progestin was thought to help protect women against heart disease. But a study from the Women's Health Initiative showed that taking estrogen plus progestin poses more risks than benefits.

These Web pages provide more information about the findings and the use of hormone therapy during and after menopause, as well as alternative approaches to treat menopausal symptoms and other conditions.

Facts About Postmenopausal Hormone Therapy - A fact sheet, which covers research findings, long- and short-term hormone use, risk factors for heart disease, breast cancer, and other conditions, and alternatives to hormone treatment

Frequently Asked Questions - Frequently asked questions about the Women's Health Initiative Estrogen Plus Progestin Study

Women's Health Initiative - The Women's Health Initiative (WHI) is a major 15-year research program to address the most common causes of death, disability and poor quality of life in postmenopausal women -- cardiovascular disease, cancer, and osteoporosis.

NIH Menopausal Hormone Therapy Information - In the summer of 2002, the Women's Health Initiative Estrogen Plus Progestin Study announced new findings that begin to offer women some guidance about hormone use.